In this paper, 18 species of the subfamilies Exogoninae, Anoplosyllinae, and Eusyllinae (Syllidae, Polychaeta) are reported from the Mediterranean Egyptian coasts, 8 of them are new records for the area: Odontosyllis fulgurans (Audouin and Milne Edwards, 1833); Syllides japonicus Imajima, 1966; Salvatoria clavata (Clapare?de, 1863); Salvatoria euritmica (Sardá, 1984); Sphaerosyllis glandulata Perkins, 1981; Parapionosyllis labornica Cognetti, 1965; Sphaerosyllis sp.; and Prosphaerosyllis sp. Five species were reported previously in the area. Four species are new records for Mediterranean Sea: Palposyllis prosostoma Hartmann-Schröder, 1977; Paraehlersia weissmaniodes (Augener,1913); Streptosyllis compoyi Brito, Núñez and San Martín, 2000; and Exogone africana Hartmann-Schröder, 1974); P. weissmaniodes and Exogone africana are two widely distributed Indo-Pacific species, so they could be considered as Lessepsian migrants. Finally, one new species is described, Parapionosyllis aegyptia.