• Trypanosyllis Claparède, 1864
• Trypanosyllis (Trypanedenta) Imajima & Hartman, 1964 accepted as Trypanedenta Imajima & Hartman, 1964
• Trypanosyllis (Trypanedenta) gemmipara Johnson, 1901 accepted as Trypanedenta gemmipara (Johnson, 1901)
• Trypanosyllis (Trypanedenta) taeniaeformis (Haswell, 1886) accepted as Trypanosyllis taeniaeformis (Haswell, 1886)
• Trypanosyllis (Trypanobia) Imajima & Hartman, 1964 accepted as Trypanobia Imajima & Hartman, 1964
• Trypanosyllis (Trypanobia) asterobia Okada, 1933 accepted as Trypanobia asterobia (Okada, 1933)
• Trypanosyllis (Trypanobia) depressa (Augener, 1913) accepted as Trypanobia depressa (Augener, 1913)
• Trypanosyllis (Trypanobia) foliosa Imajima, 2003
• Trypanosyllis (Trypanoseta) Imajima & Hartman, 1964 accepted as Haplosyllis Langerhans, 1879
• Trypanosyllis (Trypanoseta) ohma Imajima & Hartman, 1964 accepted as Haplosyllis ohma (Imajima & Hartman, 1964)
• Trypanosyllis (Trypanosyllis)
• Trypanosyllis (Trypanosyllis) coeliaca Claparède, 1868 accepted as Pseudosyllis brevipennis Grube, 1863
• Trypanosyllis (Trypanosyllis) coeliaca nipponica Imajima & Hartman, 1964
• Trypanosyllis (Trypanosyllis) hawaiiensis Hartmann-Schröder, 1978
• Trypanosyllis adamanteus Treadwell, 1914 accepted as Syllis adamantea (Treadwell, 1914)
• Trypanosyllis aeolis Langerhans, 1879
• Trypanosyllis agilis (Verrill, 1882)
• Trypanosyllis ankyloseta Day, 1960
• Trypanosyllis asterobia Okada, 1933 accepted as Trypanobia asterobia (Okada, 1933)
• Trypanosyllis attenuata Verrill, 1900
• Trypanosyllis aurantiacus Nogueira & Fukuda, 2008
• Trypanosyllis bidentata Hartman, 1967
• Trypanosyllis brevicirrata Uschakov, 1950
• Trypanosyllis californiensis Álvarez-Campos & Rouse in Álvarez-Campos, Giribet, San Martín, Rouse & Riesgo, 2017
• Trypanosyllis coeliaca Claparède, 1868 accepted as Pseudosyllis brevipennis Grube, 1863
• Trypanosyllis coeliaca nipponica Imajima & Hartman, 1964 represented as Trypanosyllis (Trypanosyllis) coeliaca nipponica Imajima & Hartman, 1964
• Trypanosyllis complanata (Treadwell, 1901)
• Trypanosyllis cristoboi Álvarez-Campos, Taboada, San Martín, Leiva & Riesgo, 2018
• Trypanosyllis crosslandi Potts, 1911
• Trypanosyllis devae Álvarez-Campos, Taboada, San Martín, Leiva & Riesgo, 2018
• Trypanosyllis didenkai Averincev, 1972
• Trypanosyllis dollfusi (Fauvel, 1933)
• Trypanosyllis estebani Álvarez-Campos, Taboada, San Martín, Leiva & Riesgo, 2018
• Trypanosyllis fertilis Verrill, 1900 accepted as Syllis corallicola Verrill, 1900
• Trypanosyllis foliosa Imajima, 2003
• Trypanosyllis gemmipara Johnson, 1901 accepted as Trypanedenta gemmipara (Johnson, 1901)
• Trypanosyllis gemmulifera Augener, 1918
• Trypanosyllis gigantea (McIntosh, 1885) accepted as Trypanedenta gigantea (McIntosh, 1885)
• Trypanosyllis ingens Johnson, 1902
• Trypanosyllis inglei Perkins, 1981
• Trypanosyllis intermedia Moore, 1909
• Trypanosyllis kalkin Álvarez-Campos & Verdes in Álvarez-Campos, Giribet, San Martín, Rouse & Riesgo, 2017
• Trypanosyllis krohnii Claparède, 1864
• Trypanosyllis leivai Álvarez-Campos, Riesgo & San Martín in Álvarez-Campos, Giribet, San Martín, Rouse & Riesgo, 2017
• Trypanosyllis luquei Álvarez-Campos & Verdes in Álvarez-Campos, Giribet, San Martín, Rouse & Riesgo, 2017
• Trypanosyllis luzonensis (Pillai, 1965)
• Trypanosyllis mercedesae Lucas Rodríguez, San Martín & Fiege, 2019
• Trypanosyllis microdenticulata Salcedo Oropeza, San Martín & Solís-Weiss, 2011
• Trypanosyllis migueli Álvarez-Campos, Taboada, San Martín, Leiva & Riesgo, 2018
• Trypanosyllis misakiensis Izuka, 1906 accepted as Trypanosyllis aeolis Langerhans, 1879
• Trypanosyllis occipitalis Hutton, 1904 in Augener, 1913 accepted as Odontosyllis polycera (Schmarda, 1861)
• Trypanosyllis parazebra Hartmann-Schröder, 1965
• Trypanosyllis parvidentata Perkins, 1981
• Trypanosyllis picta (Kinberg, 1866) accepted as Syllis picta (Kinberg, 1866)
• Trypanosyllis prampramensis Augener, 1918
• Trypanosyllis richardi Gravier, 1900 accepted as Trypanosyllis taeniaeformis (Haswell, 1886)
• Trypanosyllis rosea (Grube, 1863) accepted as Pseudosyllis brevipennis Grube, 1863
• Trypanosyllis sanchezi Álvarez-Campos, Taboada, San Martín, Leiva & Riesgo, 2018
• Trypanosyllis sanmartini Çinar, 2007
• Trypanosyllis savagei Perkins, 1981
• Trypanosyllis striata Perejaslavtseva, 1891
• Trypanosyllis taboadai Álvarez-Campos, Riesgo & San Martín in Álvarez-Campos, Giribet, San Martín, Rouse & Riesgo, 2017
• Trypanosyllis taeniaeformis (Haswell, 1886)
• Trypanosyllis tenella Verrill, 1900
• Trypanosyllis troll Ramos, San Martín & Sikorski, 2010
• Trypanosyllis uncinigera Hartmann-Schröder, 1960 accepted as Branchiosyllis exilis (Gravier, 1900)
• Trypanosyllis vittigera Ehlers, 1887
• Trypanosyllis zebra (Grube, 1860)