• Adipicola Dautzenberg, 1927
• Admytilus Berezovsky, 2015 †
• Adula H. Adams & A. Adams, 1857
• Amygdalum Megerle von Mühlfeld, 1811
• Arcomytilus Agassiz, 1842 †
• Arcoperna Conrad, 1865 †
• Arcuatula Jousseaume in Lamy, 1919
• Arenifodiens B. R. Wilson, 2006
• Arvella Bartsch in Scarlato, 1960
• Assytilus Berezovsky, 2015 †
• Aulacomya Mörch, 1853
• Bathymodiolus Kenk & B. R. Wilson, 1985
• Benthomodiolus Dell, 1987
• Botula Mörch, 1853
• Brachidontes Swainson, 1840
• Choromytilus Soot-Ryen, 1952
• Ciboticola Iredale, 1939
• Crenella T. Brown, 1827
• Crenomytilus Soot-Ryen, 1955
• Dacrydium Torell, 1859
• Exosiperna Iredale, 1929
• Fungiacava T. F. Goreau, N. I. Goreau, Neumann & Yonge, 1968
• Geukensia Van de Poel, 1959
• Gigantidas Cosel & B. A. Marshall, 2003
• Gregariella Monterosato, 1883
• Idas Jeffreys, 1876
• Inoperna Conrad, 1873 †
• Ischadium Jukes-Browne, 1905
• Jolya Bourguignat, 1877
• Leiosolenus Carpenter, 1857
• Limnoperna Rochebrune, 1882
• Lioberus Dall, 1898
• Lithophaga Röding, 1798
• Lycettia Cox, 1937 †
• Modiolatus Jousseaume, 1893
• Modiolula Sacco, 1897
• Modiolus Lamarck, 1799
• Musculus Röding, 1798
• Mytella Soot-Ryen, 1955
• Mytilaster Monterosato, 1884
• Mytilisepta Habe, 1951
• Mytilus Linnaeus, 1758
• Paramusculus Kadolsky, 1989 †
• Perna Philipsson, 1788
• Perumytilus Olsson, 1961
• Regulifer Fürsich & Werner, 1988 †
• Rhomboidella Monterosato, 1884
• Samiolus Kiel & Taviani, 2017 †
• Semimytilus Soot-Ryen, 1955
• Septifer Récluz, 1848
• Sinomytilus Thiele, 1934
• Solamen Iredale, 1924
• Stavelia Gray, 1858
• Tamu Gustafson, R. D. Turner, Lutz & Vrijenhoek, 1998
• Terua Dall, Bartsch & Rehder, 1938
• Trichomya Ihering, 1900
• Urumella Hayami & Kase, 1993
• Vilasina Bartsch in Scarlato, 1960
• Vulcanidas Cosel & B. A. Marshall, 2010
• Xenostrobus B. R. Wilson, 1967
• Zelithophaga Finlay, 1926