This paper reports on deep water Pyramidellidae from the tropical South Pacific, collected during the Tropical Deep-Sea Benthos expeditions conducted by IRD and MNHN in New Caledonia, the Solomon Islands, Fiji, Tonga, Vanuatu, Wallis and Futuna, and French Polynesian, and deals more specifically with those species that can be included in the tribe Turbonillini. Since the different genera have not been thoroughly revised at the present time and there is no certainty about their validity, we have employed only the genus name Turbonilla in a broad sense. In total, 272 species are studied, of which 30 were already known, 33 were too poorly represented to be named and are presented as sp., and 209 are described as new to science. There is a clear decrease in species richness from the Solomon Islands (202 species) eastwards to Fiji (82 species), New Caledonia (85 species), Vanuatu (31 species), Tonga (11 species) and the Marquesas (7 species). Replacement names are proposed for Turbonilla gracilis (A. Adams, 1854) non Turbo gracilis Brocchi, 1814, and Exesilla sulcata Laseron, 1959, non Odostomia sulcata Garrett, 1873, both secondary homonyms in Turbonilla. New taxonomic opinions in this work are the following: Turbonilla theresa Thiele, 1925 and Pyrgiscus mirandus Saurin, 1959 are considered synonyms of Turbonilla funiculata de Folin, 1868; Odontostomia robusta Hedley, 1899, Turbonilla microscopica Laseron, 1959, and Turbonilla (Pyrgostelis) manorae Melvill, 1898 are considered synonyms of Turbonilla mumia (A. Adams, 1861); Turbonilla decussata Pease, 1861, T. elongata Pease, 1868, Proto cornelliana Newcomb, 1870, Chemnitzia coppingeri E. A Smith, 1884, Turbonilla (Lancella) bella Dall & Bartsch, 1906, and Turbonilla (Lancella) vitiensis Pilsbry, 1917 are considered synonyms of Turbonilla varicosa (A. Adams, 1855); Elusa secunda Saurin, 1959 is a synonym of Turbonilla ovalis de Folin, 1868; Turbonilla multigyrata Dunker, 1882 is a synonym of T. candida A. Adams, 1855; Turbonilla lydia Thiele, 1925 is a synonym of Turbonilla crystallina Dall & Bartsch, 1906. Lectotypes are designated for the following nominal species: . Turbonilla acicularis (A. Adams, 1855), T. angustissima Melvill, 1904, T. amalia Thiele, 1925, T. approximata Dall & Bartsch, 1906, T. crystallina Dall & Bartsch, 1906, T. cubitata de Folin, 1868, T enelata (Melvill, 1910), T. fischeri (E. A. Smith, 1891), T. hadwigis Thiele, 1925, T. hertha Thiele, 1925, T. integra (Saurin, 1959), T. martha Thiele, 1925, T. nicobarica Thiele, 1925, T. ovalis de Folin, 1868, T. pachypleura Melvill, 1910, T. quaestuosa Melvill, 1910, T. scitula A. Adams, 1861, T. terebrina Melvill, 1896 and T. thielei (van Aartsen & Corgan, 1996).